2-Methyltetrahydrofuran (2-MeTHF, CAS No. 96-47-9) serves as a process solvent in pharmaceutical, fine chemical, and electronic chemical manufacturing. Process teams select it when they need efficient extraction, clean phase separation, and stable behavior in organometallic catalyzed and biphasic reactions.
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Property
Specification
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Chemical name
2-Methyltetrahydrofuran
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Abbreviation
2-MeTHF
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Molecular formula
C5H10O
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Molecular weight
86.13 g/mol
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Appearance
Clear, colorless liquid
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Typical purity
≥ 99.0% depending on grade
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Boiling point
approx. 80 C
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Density at 20 oC
approx. 0.85 g/cm3
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Water solubility
Limited, biphasic behavior
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REACH status
REACH-compliant grades available
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Typical supply
Bulk and packaged, subject to specification
Compared with tetrahydrofuran, this solvent supports higher product recovery and reduces solvent losses during aqueous workup. Its physicochemical profile also fits development programs that target alternative fuels or electrolytic systems for lithium electrodes in battery research. Chemists value predictable handling, consistent quality, and compatibility with established ether-based reaction platforms.
2-MeTHF supports demanding reaction environments in laboratory, pilot, and production settings. The solvent tolerates Grignard chemistry, lithium and magnesium reagents, and catalytic systems that require stable ethers under controlled conditions. Limited miscibility with water simplifies downstream separations and drying steps, which often shortens cycle times in pharmaceutical synthesis.
Typical application areas include:
In solvent selection studies, teams often assess n-Heptane alongside 2-Methyltetrahydrofuran to define polarity ranges and solvent exchange strategies. Standard storage and handling practices support safe and stable use in industrial settings.
Requests for 2-MeTHF (CAS No. 96-47-9) usually involve more than availability. Procurement and process engineers require clarity on purity grades, trace impurities, and regulatory alignment. REACH compliance plays a central role for EU-based operations, especially in pharmaceutical and electronic chemical supply chains.
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A product data sheet is available upon request, subject to application scope and supplier documentation.